Activists say the chemical industry needs to switch from petrochemical building blocks such as methanol to safer, biobased substances, Chemical & Engineering News reports. Substances that are not derived from fossil fuels should replace benzene, butadiene, ethylene, methanol, propylene, toluene, and xylene, according to a report by the group Coming Clean, a U.S.-based network of community activists, environmental justice organizations, and policy, science and market experts. Such a shift would be a major change for south Louisiana, where the petrochemical industry has grown over the past decade. In Baton Rouge, for example, ExxonMobil is in the middle of a $500 million production capacity upgrade at its polyolefins plant.